As the city is locked down under quarantine, Alice joins a small band of elite soldiers, enlisted to rescue the missing daughter of the creator of the mutating T-virus. It’s a heart-pounding race against time as the group faces off against hordes of blood- thirsty zombies, stealthy Lickers, mutant canines and the most sinister foe yet.

Picking up immediately after the events in Resident Evil: Retribution, Alice (Milla Jovovich) is the only survivor of what was meant to be humanity’s final stand against the undead. Now, she must return to where the nightmare began – The Hive in Raccoon City, where the Umbrella Corporation is gathering its forces for a final strike against the only remaining survivors of the apocalypse.